Paul M Vanhoutte Selected Research

CAY 10580

1/2018

EP4 emerges as a novel regulator of bile acid synthesis and its activation protects against hypercholesterolemia.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Paul M Vanhoutte Research Topics

Disease

26	Hypertension (High Blood Pressure) 01/2019 - 06/2004
20	Obesity 11/2017 - 03/2008
19	Inflammation (Inflammations) 11/2020 - 09/2008
16	Atherosclerosis 01/2019 - 04/2003
14	Cardiovascular Diseases (Cardiovascular Disease) 01/2019 - 06/2009
12	Insulin Resistance 10/2016 - 02/2009
10	Hypoxia (Hypoxemia) 11/2018 - 05/2009
6	Vascular Diseases (Vascular Disease) 02/2016 - 03/2008
5	Heart Failure 01/2019 - 06/2004
5	Body Weight (Weight, Body) 01/2018 - 02/2012
5	Hyperglycemia 05/2015 - 06/2009
5	Myocardial Ischemia (Ischemic Heart Diseases) 10/2013 - 04/2010
4	Ischemia 01/2020 - 06/2004
4	Myocardial Infarction 01/2020 - 01/2005
4	Metabolic Syndrome (Dysmetabolic Syndrome X) 11/2017 - 12/2012
3	Infarction (Infarctions) 01/2020 - 10/2013
3	Hypercholesterolemia 01/2018 - 01/2002
3	Endotoxemia 06/2016 - 08/2011
3	Diabetes Mellitus 01/2016 - 01/2010
3	Dyslipidemias (Dyslipidemia) 05/2015 - 01/2012
3	Thrombosis (Thrombus) 04/2013 - 01/2010
3	Hyperplasia 03/2005 - 09/2002
3	Fibrosis (Cirrhosis) 01/2005 - 02/2004
2	Weight Loss (Weight Reduction) 01/2018 - 03/2015
2	Sepsis (Septicemia) 12/2015 - 06/2004
2	Glucose Intolerance 05/2015 - 02/2009
2	Hypothyroidism 01/2015 - 06/2014
2	Pulmonary Arterial Hypertension 11/2014 - 10/2012
2	Atrial Fibrillation 12/2011 - 05/2008
2	Neoplasms (Cancer) 01/2011 - 04/2010
2	Coronary Artery Disease (Coronary Atherosclerosis) 11/2010 - 01/2002
2	Hyperhomocysteinemia 09/2006 - 03/2005

Drug/Important Bio-Agent (IBA)

16	Nitric Oxide (Nitrogen Monoxide)FDA Link 03/2018 - 09/2002
9	Proteins (Proteins, Gene)FDA Link 06/2016 - 05/2009
8	Pharmaceutical PreparationsIBA 01/2019 - 01/2002
8	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 03/2018 - 02/2008
7	Sirtuin 1IBA 01/2019 - 08/2012
7	Thromboxane Receptors (Thromboxane Receptor)IBA 11/2014 - 02/2005
6	AdipokinesIBA 01/2020 - 01/2010
6	AdiponectinIBA 03/2012 - 03/2008
5	CholesterolIBA 02/2020 - 04/2010
5	Vasodilator Agents (Vasodilators)IBA 01/2019 - 04/2010
5	Soluble Guanylyl CyclaseIBA 11/2018 - 08/2010
5	Lipocalin-2IBA 01/2018 - 04/2010
5	LipidsIBA 05/2015 - 01/2010
4	Fatty Acid-Binding ProteinsIBA 01/2020 - 04/2010
4	Vasoconstrictor AgentsIBA 01/2019 - 08/2010
4	EnzymesIBA 11/2018 - 04/2010
4	AldosteroneIBA 01/2018 - 06/2004
4	Angiotensin IIIBA 01/2018 - 01/2005
4	Biomarkers (Surrogate Marker)IBA 01/2018 - 02/2009
4	NG-Nitroarginine Methyl Ester (L-NAME)IBA 12/2015 - 01/2002
4	Glucose (Dextrose)FDA LinkGeneric 10/2013 - 02/2009
4	Insulin (Novolin)FDA Link 11/2011 - 05/2009
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2020 - 05/2009
3	LipopolysaccharidesIBA 01/2018 - 09/2008
3	SaltsIBA 01/2018 - 03/2006
3	ProstaglandinsIBA 04/2017 - 02/2008
3	Endothelin-1 (Endothelin 1)IBA 10/2016 - 01/2011
3	CytokinesIBA 06/2016 - 04/2010
3	EndotoxinsIBA 06/2016 - 07/2013
3	Arginine (L-Arginine)FDA Link 01/2016 - 04/2010
3	rho-Associated KinasesIBA 01/2016 - 05/2009
3	Acetylcysteine (Siran)FDA LinkGeneric 10/2013 - 02/2012
3	Isoproterenol (Isoprenaline)FDA LinkGeneric 01/2005 - 02/2004
2	Tight Junction ProteinsIBA 01/2020 - 06/2016
2	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2020 - 05/2009
2	Cyclic GMPIBA 11/2018 - 12/2011
2	thymoquinoneIBA 11/2018 - 12/2015
2	Prostaglandin E Receptors (Prostaglandin E Receptor)IBA 01/2018 - 12/2015
2	Triglycerides (Triacylglycerol)IBA 11/2017 - 10/2013
2	Inosine FDA Link 01/2017 - 06/2015
2	Apolipoproteins E (ApoE)IBA 06/2016 - 04/2010
2	ApolipoproteinsIBA 06/2016 - 08/2012
2	ChemokinesIBA 06/2016 - 02/2015
2	Biotin (Vitamin H)FDA Link 05/2015 - 01/2013
2	CollagenIBA 05/2015 - 07/2002
2	EP4 Subtype Prostaglandin E ReceptorsIBA 02/2015 - 02/2012
2	15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic AcidIBA 02/2014 - 12/2011
2	CalciumIBA 11/2013 - 12/2011
2	Allopurinol (Remid)FDA LinkGeneric 10/2013 - 01/2013
2	Streptozocin (Streptozotocin)FDA Link 10/2013 - 02/2012
2	Heme Oxygenase-1IBA 01/2013 - 09/2012
2	AntioxidantsIBA 01/2013 - 02/2012
2	erucylphosphocholineIBA 09/2012 - 11/2010
2	acacetinIBA 12/2011 - 05/2008
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 08/2011 - 10/2010
2	Rosiglitazone (Avandia)FDA Link 07/2011 - 11/2010
2	Epoprostenol (Prostacyclin)FDA LinkGeneric 03/2011 - 02/2009
2	Nitric Oxide Synthase (NO Synthase)IBA 08/2010 - 04/2003
2	Fibrinolytic Agents (Antithrombotic Agents)IBA 05/2010 - 04/2010
2	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 05/2010 - 02/2008
2	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 04/2010 - 04/2010
2	ThromboxanesIBA 01/2010 - 02/2008
2	endothelium-dependent hyperpolarization factor (EDHF)IBA 07/2009 - 06/2004
2	PotassiumIBA 05/2008 - 03/2006
2	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2005 - 02/2004

Therapy/Procedure

6	Therapeutics 02/2016 - 02/2009
5	Heart Transplantation (Grafting, Heart) 02/2012 - 01/2002
2	Gastric Bypass (Roux-en-Y Gastric Bypass) 11/2017 - 03/2015